BTG4, a maternal mRNA cleaner
نویسندگان
چکیده
منابع مشابه
BTG4 is a key regulator for maternal mRNA clearance during mouse early embryogenesis.
Dear Editor, The maternal to zygotic transition (MZT) is a crucial process in the early development of almost all animals, during which maternal mRNAs are degraded and the zygotic genome is activated (Li et al., 2013). How maternal mRNAs are degraded is one of the long-standing questions in the field of developmental and reproductive biology. Recently, high-throughput sequencing and genetic stu...
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Once every menstrual cycle, eggs are ovulated into the oviduct where they await fertilization. The ovulated eggs are arrested in metaphase of the second meiotic division, and only complete meiosis upon fertilization. It is crucial that the maintenance of metaphase arrest is tightly controlled, because the spontaneous activation of the egg would preclude the development of a viable embryo (Zhang...
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ژورنال
عنوان ژورنال: Journal of Molecular Cell Biology
سال: 2016
ISSN: 1674-2788,1759-4685
DOI: 10.1093/jmcb/mjw031